Mechanism of Action
Hemostatic Drug Info
Search the site
Structure of human factor VIIa and its implications for the triggering of blood coagulation.
Recombinant factor VIIa does not induce hypercoagulability in vitro.
Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa.
Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity.
Effects of binding of ligand (FVIIa) to induced tissue factor in human endothelial cells.
Cellular consequences upon factor VIIa binding to tissue factor.
Physiological function of tissue factor pathway inhibitor and interaction with heparins.
Structure of human coagulation activated factor VII.
Overall experience with NovoSeven.
NovoSeven as a universal haemostatic agent.
Epsilon-aminocaproic acid inhibits the activity of factor VIII inhibitors in patients with severe haemophilia A in vivo and in vitro.
Ability of recombinant factor VIIa to generate thrombin during inhibition of tissue factor in human subjects.
© Copyright 2002-2018 ~
All rights reserved.